To check for vapor lock, when it happens, pull over right away and shut everything off. Are you running a Holley 4BBL? Have a paint can plastic top with you and remove the air cleaner. Pull off one of the front-lower bowl screws while holding the paint cap under it to catch any fuel spilling out. See if anything comes out.
If you have vapor lock, not much will come out.
Change your needle and seat and check your float level before continuing. (VITON RUBBER NEEDLES STICK CLOSED)
If it's vapor lock. Install Fuel lines and vapor separator that the 440-6 and Hemis used.
Run a new 3/8" fuel line and a 1/4" return line, get a new 3/8 pickup and sock (has the return line fitting), Install the fuel filter that has the 3 connections on it. 1 for fuel in, 1 for fuel to the carbs,1 tiny one for the return line. Install the HIPO fuel pump that 440 and Hemis use. It'll have screws showing all the way around the base. (Carter, Holley, etc.) That'll fix it. Whe you order your fuel lines, get the set of clamps to hold them to the car. This way, fuel always circulates through the lines and doesn't "sit" next to the exhaust.
This is the same thing you can do if you run out of fuel while jumping on it.
I've had both problems.
Rob