Not sure what you're planning on using the car for, but anything in the 4's is serious draggin'. I've got a 340 e body with .474 lift 280 deg purple cam, 10:1 pistons, ported, polished, M1 Mopar manifold, balanced internally, 670 Holley carb, MSD ignition system, 727 trans with kevlar clutches, valve body regulator change for full clamp load to the clutches for capacity, shift kit, 170K stall convertor, 3.91 Richmond gear, and Auburn grip in the 8 3/4 " rear.... Lemme tell you, I'm thinkin' of movin' down to a 3.23 ratio for a cruiser... The 3.91 and converter combo makes it tuff to even hook up in first! High revs on the freeway... But gets there quick! My recommendation is build your engine for good low end torque. Then you don't need to rely on gear multiplication for the torque, and won't be stuck with such a high ratio on the freeways..... Of course, if you're tubbed with slicks, wheelie bars, and a monster engine for the 1/8 or 1/4 mile.... I know a guy running a ratio in the 5's!