I have tried them, but I prefer the good ol' fashioned high VOC stuff!! Nothin' like good ol Volatile Organic Compounds to get you goin' in the morning.
Personally, when I spend 200+ hours on prepwork on a project car, I don't want to risk laying down a paint job that may or may not hold up. My experience with the water based stuff is that it tends to delam sooner than good old urethanes do.