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Flash vs. Performance - 6 barrel is mostly for showing off, more unique, and more difficult to keep in tune - 4 barrel is easier to set up, cheaper, and will out perform it on the street but there are a million of them out there.
6 Barrel Throttle Body with EFI
If you have a 6 pack already then go for it. Properly tuned a 6 pack will perform as well or better than any 4 barrel "on the street". Full blown race then a four barrel but on the street the 6 pack works fine. I run a 512 stroker with a 6 pack at 622 plus hp. Runs crisp, idles great at 1100 (kinda big cam) and pulls like a freight train. Slams you back when the end carbs open and NOTHING sounds better than those end carbs screaming!