they should both be turned at the same time basically 1 after the other , each controls 4 of the 8 cylinders , both do the same thing though , sounds to me like you have other problems , it shouldn`t make enough difference to cause the engine to run rich enough to have black smoke pour out he exhuast
counterclockwise richens thew mix & clockwise leans it , as Oldschool said start with both screw about 1.5 turnsout from the bottom