Can you post a pic of the lifter base? If the entire base is cup shapped, and the hole is centered, the lifter was rotating. So possibly somethign caused the oil film to break down. If the lifter has a hole in the center, but is basically flat, it wasnt rotating much if at all. That will kill it very fast. It's hard to say why a lobe is lost these days. All you can do is everything possible. I would definately look at the whoel engien. You got iron all thru it at this point.