I'm running a 360 based 408 stroker. My block required no clearancing whatsoever. I'm using KB hyper pistons, Eagle SIR rods, and a Mopar 4" cast crank, all internally balanced. The top end uses an Eddy RPM Air Gap intake, 800cfm Thunder AVS dual feed carb, Performer RPM cam kit, and Performer RPM heads. I built it myself, but had the machine work done for me. I have about 3000 hard street miles on it right now, now problems as far as engine health. It runs fine on pump gas too. My motor needs a bigger/better cam and head work though, it runs out of steam around 5K. Plenty of torque too, perfect for a street motor.
The strokers can turn RPM's too, they just need more airflow. They can make the same or more power as a stock stroke engine, it'll just peak out much lower with the same components. I can't tell you how it compares to stock since this engine replaced a weak, worn out, bone stock 318 out of a cop car.